Depression and suicide are major health problems. The therapies available today are not as effective as we would like them to be. The suicide rate is increasing. There is an urgent need for new and effective interventions for depression.
Some psychedelics can show potential as suicidal attacks. The challenge for both patients and doctors is overcoming the negative stigma associated with its use. One such challenge continues to plague widespread medical marijuana use. One promising psychedelic is psilocybin, which is found in more than 75 species of fungi. You can also buy mail order mushrooms in Canada via Microdose Prolab.
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The most famous is Psilocybe Mexicana, also known as the “magic mushroom”. Psilocybin is converted spontaneously to psilocin after ingestion; Psilocin is more lipid-soluble and is a true psychoactive agent.
Recent evidence for PET suggests that the psychoactive effects of psilocin depend on its ability to stimulate a specific serotonin receptor called 5HT2A.
So far, psilocybin has demonstrated simplicity, although some authors claim hopeful results in clinical trials for the healing of depression, post-traumatic stress disorder, addiction, and fear of death.
Various types of psilocybe mushrooms also contain amounts of beta-carboline derived from tryptophan, such as Harman and harmine, which can also have beneficial effects on brain function. Why is beta-carboline important for psilocybe mushroom to work?
Beta-carboline is a strong inhibitor of an enzyme called monoamine oxidase, which is responsible for deactivating psilocin. This is an interesting behavior of any plant or fungus. Psilocybe produces a wide variety of natural products in unique ways that differ from the same constituent ingredients.